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Strategies

Vitamin B6 and magnesium

Vitamin B6 (pyridoxine) therapy has been used since the 1960s and has been reported to improve sleep, language, attention and behaviour. It is given with magnesium to help the body use the B6. There is also evidence suggesting B6 and magnesium should be given with supplemental doses of other B group vitamins.

Vitamin B6 and magnesium
http://www.autism.org/vitaminb6.html

Combined vitamin B6-magnesium treatment in autism spectrum disorder (Cochrane Review)
http://www.cochrane.org/cochrane/revabstr/ab003497.htm

Rimland, B (1996) "Vitamin B6 in autism: the safety issue" Autism Research Review International 10 (3), 3. http://www.autism.com/ari/editorials/b6safe.html

Rimland, B (1997) "What is the right ‘dosage for vitamin B6, DMG and other nutrients useful in autism?" Autism Research Review International 11(4), 3. http://www.autism.com/ari/editorials/dosage.html

Rimland, B "Vitamin B6 (and magnesium) in the treatment of autism" Autism Research Review International, 3. http://www.autism.org/vitb6.html

Bernstein, A (1990) "Vitamin B6 in clinical neurology" Annals of the New York Academy of Sciences 585, 250-60.

Carr, I (1986) "The therapeutic use of vitamin B6 in autism" Communication 20 (2), 13-14.

Martinueau J et al (1989) "Electrophysiological effects of fenfluramine or combined vitamin B6 and magnesium on children with autistic behaviour" Developmental Medicine and Child Neurology 31 (6), 721-7.

Pfeiffer, S et al (1995) "Efficacy of vitamin B6 and magnesium in the treatment of autism: a methodology review and summary of outcomes" Journal of Autism and Developmental Disorders 25 (5), 481-93.

Rimland, B (1987) "Megavitamin B6 and magnesium in the treatment of autistic children and adults" In Neurobiological issues in autism" ed by E Schopler & G mesibov, New York, Plenum, pp 389-405.

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